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The Spi1/PU.1 transcription factor accelerates replication fork progression by increasing PP1 phosphatase in leukemia
Oncogenes trigger replicative stress that can lead to genetic instability, which participates in cancer progression. Thus, determining how cells cope with replicative stress can help our understanding of oncogenesis and lead to the identification of new antitumor treatment targets. We previously sho...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514894/ https://www.ncbi.nlm.nih.gov/pubmed/28415748 http://dx.doi.org/10.18632/oncotarget.16183 |