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The Spi1/PU.1 transcription factor accelerates replication fork progression by increasing PP1 phosphatase in leukemia

Oncogenes trigger replicative stress that can lead to genetic instability, which participates in cancer progression. Thus, determining how cells cope with replicative stress can help our understanding of oncogenesis and lead to the identification of new antitumor treatment targets. We previously sho...

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Detalles Bibliográficos
Autores principales: Rimmelé, Pauline, Esposito, Michela, Delestré, Laure, Guervilly, Jean-Hugues, Ridinger-Saison, Maya, Despras, Emmanuelle, Moreau-Gachelin, Françoise, Rosselli, Filippo, Guillouf, Christel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514894/
https://www.ncbi.nlm.nih.gov/pubmed/28415748
http://dx.doi.org/10.18632/oncotarget.16183