Cargando…
Mitochondrial matrix chaperone and c-myc inhibition causes enhanced lethality in glioblastoma
Malignant gliomas display high levels of the transcription factor c-myc and organize a tumor specific chaperone network within mitochondria. Here, we show that c-myc along with mitochondrial chaperone inhibition displays massive tumor cell death. Inhibition of mitochondrial matrix chaperones and c-m...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514897/ https://www.ncbi.nlm.nih.gov/pubmed/28415755 http://dx.doi.org/10.18632/oncotarget.16202 |