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The relevance of a low JAK2(V617F) allele burden in clinical practice: a monocentric study

Since low JAK2(V617F) allele burden (AB) has been detected also in healthy subjects, its clinical interpretation may be challenging in patients with chronic myeloproliferative neoplasms (MPNs). We tested 1087 subjects for JAK2(V617F) mutation on suspicion of hematological malignancy. Only 497 (45.7%...

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Detalles Bibliográficos
Autores principales: Perricone, Margherita, Polverelli, Nicola, Martinelli, Giovanni, Catani, Lucia, Ottaviani, Emanuela, Zuffa, Elisa, Franchini, Eugenia, Dizdari, Arbana, Forte, Dorian, Sabattini, Elena, Cavo, Michele, Vianelli, Nicola, Palandri, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514906/
https://www.ncbi.nlm.nih.gov/pubmed/28422729
http://dx.doi.org/10.18632/oncotarget.16744