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The N-terminal polypeptide derived from viral macrophage inflammatory protein II reverses breast cancer epithelial-to-mesenchymal transition via a PDGFRα-dependent mechanism

NT21MP, a 21-residue peptide derived from the viral macrophage inflammatory protein II, competed effectively with the natural ligand of CXC chemokine receptor 4 (CXCR4), stromal cell-derived factor 1-alpha, to induce apoptosis and inhibit growth in breast cancer. Its role in tumor epithelial-to-mese...

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Detalles Bibliográficos
Autores principales: Yang, Qing-Ling, Zhang, Ling-Yu, Wang, Hai-Feng, Li, Yu, Wang, Yue-Yue, Chen, Tian-Tian, Dai, Meng-Fen, Wu, Hai-Hua, Chen, Su-Lian, Wang, Wen-Rui, Wu, Qiong, Chen, Chang-Jie, Zhou, Cong-Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514921/
https://www.ncbi.nlm.nih.gov/pubmed/28415580
http://dx.doi.org/10.18632/oncotarget.16394