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Inhibition of NLRP3 inflammasome by thioredoxin-interacting protein in mouse Kupffer cells as a regulatory mechanism for non-alcoholic fatty liver disease development

NOD-like receptor (NLR) NLRP3 inflammasome activation has been implicated in the progression of non-alcoholic fatty liver disease (NAFLD) from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH). It has been also shown that palmitic acid (PA) activates NLRP3 inflammasome and pro...

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Detalles Bibliográficos
Autores principales: He, Kun, Zhu, Xiwen, Liu, Yan, Miao, Chunmu, Wang, Tao, Li, Peizhi, Zhao, Lei, Chen, Yaxi, Gong, Junhua, Cai, Can, Li, Jinzheng, Li, Shengwei, Ruan, Xiong Z., Gong, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514938/
https://www.ncbi.nlm.nih.gov/pubmed/28499273
http://dx.doi.org/10.18632/oncotarget.17489