Cargando…

Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids

The beta amyloid (Aβ) and other aggregating proteins in the brain increase with age and are frequently found within neurons. The mechanistic relationship between intracellular amyloid, aging and neurodegeneration is not, however, well understood. We use a proteotoxicity model based upon the inducibl...

Descripción completa

Detalles Bibliográficos
Autores principales: Currais, Antonio, Quehenberger, Oswald, M Armando, Aaron, Daugherty, Daniel, Maher, Pam, Schubert, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514994/
https://www.ncbi.nlm.nih.gov/pubmed/28721267
http://dx.doi.org/10.1038/npjamd.2016.12