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Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids
The beta amyloid (Aβ) and other aggregating proteins in the brain increase with age and are frequently found within neurons. The mechanistic relationship between intracellular amyloid, aging and neurodegeneration is not, however, well understood. We use a proteotoxicity model based upon the inducibl...
Autores principales: | Currais, Antonio, Quehenberger, Oswald, M Armando, Aaron, Daugherty, Daniel, Maher, Pam, Schubert, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514994/ https://www.ncbi.nlm.nih.gov/pubmed/28721267 http://dx.doi.org/10.1038/npjamd.2016.12 |
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