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It takes two to tango: NAD(+) and sirtuins in aging/longevity control
The coupling of nicotinamide adenine dinucleotide (NAD(+)) breakdown and protein deacylation is a unique feature of the family of proteins called ‘sirtuins.’ This intimate connection between NAD(+) and sirtuins has an ancient origin and provides a mechanistic foundation that translates the regulatio...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514996/ https://www.ncbi.nlm.nih.gov/pubmed/28721271 http://dx.doi.org/10.1038/npjamd.2016.17 |