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Increased oxidative phosphorylation in response to acute and chronic DNA damage

Accumulation of DNA damage is intricately linked to aging, aging-related diseases and progeroid syndromes such as Cockayne syndrome (CS). Free radicals from endogenous oxidative energy metabolism can damage DNA, however the potential of acute or chronic DNA damage to modulate cellular and/or organis...

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Detalles Bibliográficos
Autores principales: Brace, Lear E, Vose, Sarah C, Stanya, Kristopher, Gathungu, Rose M, Marur, Vasant R, Longchamp, Alban, Treviño-Villarreal, Humberto, Mejia, Pedro, Vargas, Dorathy, Inouye, Karen, Bronson, Roderick T, Lee, Chih-Hao, Neilan, Edward, Kristal, Bruce S, Mitchell, James R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514997/
https://www.ncbi.nlm.nih.gov/pubmed/28721274
http://dx.doi.org/10.1038/npjamd.2016.22