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Cysteinyl Leukotrienes in Eosinophil Biology: Functional Roles and Therapeutic Perspectives in Eosinophilic Disorders

Cysteinyl leukotrienes (cysLTs), LTC4, and its extracellular metabolites, LTD4 and LTE4, have varied and multiple roles in mediating eosinophilic disorders including host defense against parasitic helminthes and allergic inflammation, especially in the lung and in asthma. CysLTs are known to act thr...

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Detalles Bibliográficos
Autores principales: Thompson-Souza, Glaucia A., Gropillo, Isabella, Neves, Josiane S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515036/
https://www.ncbi.nlm.nih.gov/pubmed/28770202
http://dx.doi.org/10.3389/fmed.2017.00106