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Evaluation of the immunogenicity and impact on the latent HIV-1 reservoir of a conserved region vaccine, MVA.HIVconsv, in antiretroviral therapy-treated subjects

Introduction: Vaccines may be key components of a curative strategy for HIV-1. We investigated whether a novel immunogen, HIVconsv, designed to re-direct T cell responses to conserved viral epitopes, could impact the HIV-1 reservoir in chronic antiretroviral therapy (ART)-treated subjects when deliv...

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Detalles Bibliográficos
Autores principales: Hancock, Gemma, Morón-López, Sara, Kopycinski, Jakub, Puertas, Maria C., Giannoulatou, Eleni, Rose, Annie, Salgado, Maria, Hayton, Emma-Jo, Crook, Alison, Morgan, Catharine, Angus, Brian, Chen, Fabian, Yang, Hongbing, Martinez-Picado, Javier, Hanke, Tomas, Dorrell, Lucy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515041/
https://www.ncbi.nlm.nih.gov/pubmed/28537062
http://dx.doi.org/10.7448/IAS.20.1.21171