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Somatic mutations in leukocytes infiltrating primary breast cancers

BACKGROUND: Malignant transformation requires the interaction of cancer cells with their microenvironment, including infiltrating leukocytes. However, somatic mutational studies have focused on alterations in cancer cells, assuming that the microenvironment is genetically normal. Because we hypothes...

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Detalles Bibliográficos
Autores principales: Kleppe, Maria, Comen, Elizabeth, Wen, Hannah Y, Bastian, Lennart, Blum, Brian, Rapaport, Franck T, Keller, Matthew, Granot, Zvika, Socci, Nicolas, Viale, Agnès, You, Daoqi, Benezra, Robert, Weigelt, Britta, Brogi, Edi, Berger, Michael F, Reis-Filho, Jorge S, Levine, Ross L, Norton, Larry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515194/
https://www.ncbi.nlm.nih.gov/pubmed/28721364
http://dx.doi.org/10.1038/npjbcancer.2015.5