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Nuclear localization is required for Dishevelled function in Wnt/β-catenin signaling

BACKGROUND: Dishevelled (Dsh) is a key component of multiple signaling pathways that are initiated by Wnt secreted ligands and Frizzled receptors during embryonic development. Although Dsh has been detected in a number of cellular compartments, the importance of its subcellular distribution for sign...

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Detalles Bibliográficos
Autores principales: Itoh, Keiji, Brott, Barbara K, Bae, Gyu-Un, Ratcliffe, Marianne J, Sokol, Sergei Y
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC551520/
https://www.ncbi.nlm.nih.gov/pubmed/15720724
http://dx.doi.org/10.1186/jbiol20