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Tobramycin and bicarbonate synergise to kill planktonic Pseudomonas aeruginosa, but antagonise to promote biofilm survival

Increasing antibiotic resistance and the declining rate at which new antibiotics come into use create a need to increase the efficacy of existing antibiotics. The aminoglycoside tobramycin is standard-of-care for many types of Pseudomonas aeruginosa infections, including those in the lungs of cystic...

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Detalles Bibliográficos
Autores principales: Kaushik, Karishma S, Stolhandske, Jake, Shindell, Orrin, Smyth, Hugh D, Gordon, Vernita D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515257/
https://www.ncbi.nlm.nih.gov/pubmed/28721244
http://dx.doi.org/10.1038/npjbiofilms.2016.6