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Tobramycin and bicarbonate synergise to kill planktonic Pseudomonas aeruginosa, but antagonise to promote biofilm survival
Increasing antibiotic resistance and the declining rate at which new antibiotics come into use create a need to increase the efficacy of existing antibiotics. The aminoglycoside tobramycin is standard-of-care for many types of Pseudomonas aeruginosa infections, including those in the lungs of cystic...
Autores principales: | Kaushik, Karishma S, Stolhandske, Jake, Shindell, Orrin, Smyth, Hugh D, Gordon, Vernita D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515257/ https://www.ncbi.nlm.nih.gov/pubmed/28721244 http://dx.doi.org/10.1038/npjbiofilms.2016.6 |
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