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Reaction–diffusion theory explains hypoxia and heterogeneous growth within microbial biofilms associated with chronic infections

Reaction–diffusion models were applied to gain insight into the aspects of biofilm infection and persistence by comparing mathematical simulations with the experimental data from varied bacterial biofilms. These comparisons, including three in vitro systems and two clinical investigations of specime...

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Detalles Bibliográficos
Autores principales: Stewart, Philip S, Zhang, Tianyu, Xu, Ruifang, Pitts, Betsey, Walters, Marshall C, Roe, Frank, Kikhney, Judith, Moter, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515263/
https://www.ncbi.nlm.nih.gov/pubmed/28721248
http://dx.doi.org/10.1038/npjbiofilms.2016.12