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Reaction–diffusion theory explains hypoxia and heterogeneous growth within microbial biofilms associated with chronic infections
Reaction–diffusion models were applied to gain insight into the aspects of biofilm infection and persistence by comparing mathematical simulations with the experimental data from varied bacterial biofilms. These comparisons, including three in vitro systems and two clinical investigations of specime...
Autores principales: | Stewart, Philip S, Zhang, Tianyu, Xu, Ruifang, Pitts, Betsey, Walters, Marshall C, Roe, Frank, Kikhney, Judith, Moter, Annette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515263/ https://www.ncbi.nlm.nih.gov/pubmed/28721248 http://dx.doi.org/10.1038/npjbiofilms.2016.12 |
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