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DNA defects, epigenetics, and gene expression in cancer-adjacent breast: a study from The Cancer Genome Atlas

Recurrence rates after breast-conserving therapy may depend on genomic characteristics of cancer-adjacent, benign-appearing tissue. Studies have not evaluated recurrence in association with multiple genomic characteristics of cancer-adjacent breast tissue. To estimate the prevalence of DNA defects a...

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Detalles Bibliográficos
Autores principales: Troester, Melissa A, Hoadley, Katherine A, D’Arcy, Monica, Cherniack, Andrew D, Stewart, Chip, Koboldt, Daniel C, Robertson, A Gordon, Mahurkar, Swapna, Shen, Hui, Wilkerson, Matthew D, Sandhu, Rupninder, Johnson, Nicole B, Allison, Kimberly H, Beck, Andrew H, Yau, Christina, Bowen, Jay, Sheth, Margi, Hwang, E Shelley, Perou, Charles M, Laird, Peter W, Ding, Li, Benz, Christopher C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515343/
https://www.ncbi.nlm.nih.gov/pubmed/28721375
http://dx.doi.org/10.1038/npjbcancer.2016.7