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Single-molecule fluorescence imaging of RalGDS on cell surfaces during signal transduction from Ras to Ral

RalGDS is one of the Ras effectors and functions as a guanine nucleotide exchange factor for the small G-protein, Ral, which regulates membrane trafficking and cytoskeletal remodeling. The translocation of RalGDS from the cytoplasm to the plasma membrane is required for Ral activation. In this study...

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Detalles Bibliográficos
Autores principales: Yoshizawa, Ryo, Umeki, Nobuhisa, Yanagawa, Masataka, Murata, Masayuki, Sako, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515350/
https://www.ncbi.nlm.nih.gov/pubmed/28744424
http://dx.doi.org/10.2142/biophysico.14.0_75