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Single-molecule fluorescence imaging of RalGDS on cell surfaces during signal transduction from Ras to Ral
RalGDS is one of the Ras effectors and functions as a guanine nucleotide exchange factor for the small G-protein, Ral, which regulates membrane trafficking and cytoskeletal remodeling. The translocation of RalGDS from the cytoplasm to the plasma membrane is required for Ral activation. In this study...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society of Japan (BSJ)
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515350/ https://www.ncbi.nlm.nih.gov/pubmed/28744424 http://dx.doi.org/10.2142/biophysico.14.0_75 |