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Monocyte derived macrophages from CF pigs exhibit increased inflammatory responses at birth
BACKGROUND: We sought to address whether CF macrophages have a primary functional defect as a consequence of CFTR loss and thus contribute to the onset of infection and inflammation observed in CF lung disease. METHODS: Monocyte derived macrophages (MDMs) were prepared from newborn CF and non-CF pig...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515361/ https://www.ncbi.nlm.nih.gov/pubmed/28377087 http://dx.doi.org/10.1016/j.jcf.2017.03.007 |