The GalNAc-T Activation Pathway (GALA) is not a general mechanism for regulating mucin-type O-glycosylation

Mucin-type O-glycosylation is initiated by the UDP-GalNAc polypeptide:N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. Their activity results in the GalNAc α1-O-Thr/Ser structure, termed the Tn antigen, which is further decorated with additional sugars. In neoplastic cells, the Tn ant...

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Detalles Bibliográficos
Autores principales: Herbomel, Gaetan G., Rojas, Raul E., Tran, Duy T., Ajinkya, Monica, Beck, Lauren, Tabak, Lawrence A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515409/
https://www.ncbi.nlm.nih.gov/pubmed/28719662
http://dx.doi.org/10.1371/journal.pone.0179241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515409/
https://www.ncbi.nlm.nih.gov/pubmed/28719662
http://dx.doi.org/10.1371/journal.pone.0179241

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