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Predicting the protein half-life in tissue from its cellular properties

Protein half-life is an important feature of protein homeostasis (proteostasis). The increasing number of in vivo and in vitro studies using high throughput proteomics provide estimates of the protein half-lives in tissues and cells. However, protein half-lives in cells and tissues are different. Du...

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Detalles Bibliográficos
Autores principales: Rahman, Mahbubur, Sadygov, Rovshan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515413/
https://www.ncbi.nlm.nih.gov/pubmed/28719664
http://dx.doi.org/10.1371/journal.pone.0180428