Cargando…

RNA sequencing to determine the contribution of kinase receptor transactivation to G protein coupled receptor signalling in vascular smooth muscle cells

G protein coupled receptor (GPCR) signalling covers three major mechanisms. GPCR agonist engagement allows for the G proteins to bind to the receptor leading to a classical downstream signalling cascade. The second mechanism is via the utilization of the β-arrestin signalling molecule and thirdly vi...

Descripción completa

Detalles Bibliográficos
Autores principales: Kamato, Danielle, Bhaskarala, Venkata Vijayanand, Mantri, Nitin, Oh, Tae Gyu, Ling, Dora, Janke, Reearna, Zheng, Wenhua, Little, Peter J, Osman, Narin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515425/
https://www.ncbi.nlm.nih.gov/pubmed/28719611
http://dx.doi.org/10.1371/journal.pone.0180842