Cargando…

Direct measurement of conformational strain energy in protofilaments curling outward from disassembling microtubule tips

Disassembling microtubules can generate movement independently of motor enzymes, especially at kinetochores where they drive chromosome motility. A popular explanation is the ‘conformational wave’ model, in which protofilaments pull on the kinetochore as they curl outward from a disassembling tip. B...

Descripción completa

Detalles Bibliográficos
Autores principales: Driver, Jonathan W, Geyer, Elisabeth A, Bailey, Megan E, Rice, Luke M, Asbury, Charles L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515574/
https://www.ncbi.nlm.nih.gov/pubmed/28628007
http://dx.doi.org/10.7554/eLife.28433