A new Prenylated Flavonoid induces G0/G1 arrest and apoptosis through p38/JNK MAPK pathways in Human Hepatocellular Carcinoma cells

Prenylated flavonoids have been demonstrated to possess diverse bioactivities including antitumor effects. One new, daphnegiravone D (1), and four known (2–5) prenylated flavonoids were isolated from Daphne giraldii. Their cytotoxic activities revealed that daphnegiravone D markedly inhibited the pr...

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Detalles Bibliográficos
Autores principales: Wang, Di, Sun, Qian, Wu, Jie, Wang, Wei, Yao, Guodong, Li, Tianyang, Li, Xue, Li, Lingzhi, Zhang, Yan, Cui, Wei, Song, Shaojiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515844/
https://www.ncbi.nlm.nih.gov/pubmed/28720813
http://dx.doi.org/10.1038/s41598-017-05955-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515844/
https://www.ncbi.nlm.nih.gov/pubmed/28720813
http://dx.doi.org/10.1038/s41598-017-05955-0

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