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A new Prenylated Flavonoid induces G0/G1 arrest and apoptosis through p38/JNK MAPK pathways in Human Hepatocellular Carcinoma cells
Prenylated flavonoids have been demonstrated to possess diverse bioactivities including antitumor effects. One new, daphnegiravone D (1), and four known (2–5) prenylated flavonoids were isolated from Daphne giraldii. Their cytotoxic activities revealed that daphnegiravone D markedly inhibited the pr...
Autores principales: | Wang, Di, Sun, Qian, Wu, Jie, Wang, Wei, Yao, Guodong, Li, Tianyang, Li, Xue, Li, Lingzhi, Zhang, Yan, Cui, Wei, Song, Shaojiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515844/ https://www.ncbi.nlm.nih.gov/pubmed/28720813 http://dx.doi.org/10.1038/s41598-017-05955-0 |
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