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Effect of head group and lipid tail oxidation in the cell membrane revealed through integrated simulations and experiments
We report on multi-level atomistic simulations for the interaction of reactive oxygen species (ROS) with the head groups of the phospholipid bilayer, and the subsequent effect of head group and lipid tail oxidation on the structural and dynamic properties of the cell membrane. Our simulations are va...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515852/ https://www.ncbi.nlm.nih.gov/pubmed/28720839 http://dx.doi.org/10.1038/s41598-017-06412-8 |