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Effect of head group and lipid tail oxidation in the cell membrane revealed through integrated simulations and experiments

We report on multi-level atomistic simulations for the interaction of reactive oxygen species (ROS) with the head groups of the phospholipid bilayer, and the subsequent effect of head group and lipid tail oxidation on the structural and dynamic properties of the cell membrane. Our simulations are va...

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Detalles Bibliográficos
Autores principales: Yusupov, M., Wende, K., Kupsch, S., Neyts, E. C., Reuter, S., Bogaerts, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515852/
https://www.ncbi.nlm.nih.gov/pubmed/28720839
http://dx.doi.org/10.1038/s41598-017-06412-8

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