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Coronavirus nucleocapsid proteins assemble constitutively in high molecular oligomers

Coronaviruses (CoV) are enveloped viruses and rely on their nucleocapsid N protein to incorporate the positive-stranded genomic RNA into the virions. CoV N proteins form oligomers but the mechanism and relevance underlying their multimerization remain to be fully understood. Using in vitro pull-down...

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Detalles Bibliográficos
Autores principales: Cong, Yingying, Kriegenburg, Franziska, de Haan, Cornelis A. M., Reggiori, Fulvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515880/
https://www.ncbi.nlm.nih.gov/pubmed/28720894
http://dx.doi.org/10.1038/s41598-017-06062-w