Metformin ameliorates the Phenotype Transition of Peritoneal Mesothelial Cells and Peritoneal Fibrosis via a modulation of Oxidative Stress

Phenotype transition of peritoneum is an early mechanism of peritoneal fibrosis. Metformin, 5′-adenosine monophosphate-activated protein kinase (AMPK) activator, has recently received a new attention due to its preventive effect on organ fibrosis and cancer metastasis by inhibiting epithelial-to-mes...

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Detalles Bibliográficos
Autores principales: Shin, Hyun-Soo, Ko, Jiyeon, Kim, Dal-Ah, Ryu, Eun-Sun, Ryu, Hye-Myung, Park, Sun-Hee, Kim, Yong-Lim, Oh, Eok-Soo, Kang, Duk-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515908/
https://www.ncbi.nlm.nih.gov/pubmed/28720775
http://dx.doi.org/10.1038/s41598-017-05836-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515908/
https://www.ncbi.nlm.nih.gov/pubmed/28720775
http://dx.doi.org/10.1038/s41598-017-05836-6

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