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Knowledge-transfer learning for prediction of matrix metalloprotease substrate-cleavage sites

Matrix Metalloproteases (MMPs) are an important family of proteases that play crucial roles in key cellular and disease processes. Therefore, MMPs constitute important targets for drug design, development and delivery. Advanced proteomic technologies have identified type-specific target substrates;...

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Detalles Bibliográficos
Autores principales: Wang, Yanan, Song, Jiangning, Marquez-Lago, Tatiana T., Leier, André, Li, Chen, Lithgow, Trevor, Webb, Geoffrey I., Shen, Hong-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515926/
https://www.ncbi.nlm.nih.gov/pubmed/28720874
http://dx.doi.org/10.1038/s41598-017-06219-7