Cargando…

Knowledge-transfer learning for prediction of matrix metalloprotease substrate-cleavage sites

Matrix Metalloproteases (MMPs) are an important family of proteases that play crucial roles in key cellular and disease processes. Therefore, MMPs constitute important targets for drug design, development and delivery. Advanced proteomic technologies have identified type-specific target substrates;...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yanan, Song, Jiangning, Marquez-Lago, Tatiana T., Leier, André, Li, Chen, Lithgow, Trevor, Webb, Geoffrey I., Shen, Hong-Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515926/ https://www.ncbi.nlm.nih.gov/pubmed/28720874 http://dx.doi.org/10.1038/s41598-017-06219-7

Ejemplares similares

Procleave: Predicting Protease-specific Substrate Cleavage Sites by Combining Sequence and Structural Information
por: Li, Fuyi, et al.
Publicado: (2020)

PhosTransfer: A Deep Transfer Learning Framework for Kinase-Specific Phosphorylation Site Prediction in Hierarchy
por: Xu, Ying, et al.
Publicado: (2020)

PhosphoPredict: A bioinformatics tool for prediction of human kinase-specific phosphorylation substrates and sites by integrating heterogeneous feature selection
por: Song, Jiangning, et al.
Publicado: (2017)

BastionHub: a universal platform for integrating and analyzing substrates secreted by Gram-negative bacteria
por: Wang, Jiawei, et al.
Publicado: (2020)

iProt-Sub: a comprehensive package for accurately mapping and predicting protease-specific substrates and cleavage sites
por: Song, Jiangning, et al.
Publicado: (2018)

PROSPER: An Integrated Feature-Based Tool for Predicting Protease Substrate Cleavage Sites
por: Song, Jiangning, et al.
Publicado: (2012)

Stochastic adaptation and fold-change detection: from single-cell to population behavior
por: Marquez-Lago, Tatiana T, et al.
Publicado: (2011)

Delay chemical master equation: direct and closed-form solutions
por: Leier, Andre, et al.
Publicado: (2015)

Degradation of small leucine-rich repeat proteoglycans by matrix metalloprotease-13: identification of a new biglycan cleavage site
por: Monfort, Jordi, et al.
Publicado: (2006)

Site specificity determinants for prelamin A cleavage by the zinc metalloprotease ZMPSTE24
por: Babatz, Timothy D., et al.
Publicado: (2020)

Probability distributed time delays: integrating spatial effects into temporal models
por: Marquez-Lago, Tatiana T, et al.
Publicado: (2010)

Exact model reduction with delays: closed-form distributions and extensions to fully bi-directional monomolecular reactions
por: Leier, Andre, et al.
Publicado: (2014)

The Spatial Chemical Langevin Equation and Reaction Diffusion Master Equations: moments and qualitative solutions
por: Ghosh, Atiyo, et al.
Publicado: (2015)

Correction: Degradation of small leucine-rich repeat proteoglycans by matrix metalloprotease 13 - identification of a new biglycan cleavage site
por: Monfort, Jordi, et al.
Publicado: (2013)

Defining substrate requirements for cleavage of farnesylated prelamin A by the integral membrane zinc metalloprotease ZMPSTE24
por: Wood, Kaitlin M., et al.
Publicado: (2020)

Positive-unlabelled learning of glycosylation sites in the human proteome
por: Li, Fuyi, et al.
Publicado: (2019)

Intracellular Cleavage of the Cx43 C-Terminal Domain by Matrix-Metalloproteases: A Novel Contributor to Inflammation?
por: De Bock, Marijke, et al.
Publicado: (2015)

Physiology and pathophysiology of matrix metalloproteases
por: Klein, T., et al.
Publicado: (2010)

BigFiRSt: A Software Program Using Big Data Technique for Mining Simple Sequence Repeats From Large-Scale Sequencing Data
por: Chen, Jinxiang, et al.
Publicado: (2022)

The selectivity of galardin and an azasugar-based hydroxamate compound for human matrix metalloproteases and bacterial metalloproteases
por: Sylte, Ingebrigt, et al.
Publicado: (2018)

The crystal structure of the TonB-dependent transporter YncD reveals a positively charged substrate-binding site
por: Grinter, Rhys, et al.
Publicado: (2020)

A Role for Matrix Metalloproteases in Antidepressant Efficacy
por: Alaiyed, Seham, et al.
Publicado: (2019)

Matrix Metalloproteases as Influencers of the Cells’ Social Media
por: Young, Daniel, et al.
Publicado: (2019)

Targeting matrix metalloproteases in diabetic wound healing
por: Chen, Junren, et al.
Publicado: (2023)

SVM-based prediction of caspase substrate cleavage sites
por: Wee, Lawrence JK, et al.
Publicado: (2006)

Cohesin cleavage by separase is enhanced by a substrate motif distinct from the cleavage site
por: Rosen, Laura E., et al.
Publicado: (2019)

Do Matrix Metalloproteases and Tissue Inhibitors of Metalloproteases in Tenocytes of the Rotator Cuff Differ with Varying Donor Characteristics?
por: Klatte-Schulz, Franka, et al.
Publicado: (2015)

Cleavage of model substrates by archaeal RNase P: role of protein cofactors in cleavage-site selection
por: Sinapah, Sylvie, et al.
Publicado: (2011)

Evaluation of indomethacin as matrix metalloproteases inhibitor in human dentin
por: Shailendra, Mashalkar, et al.
Publicado: (2019)

Corrigendum: Targeting matrix metalloproteases in diabetic wound healing
por: Chen, Junren, et al.
Publicado: (2023)

Epidermal Integrin α3β1 Regulates Tumor-Derived Proteases BMP-1, Matrix Metalloprotease-9, and Matrix Metalloprotease-3
por: Longmate, Whitney M., et al.
Publicado: (2021)

Matrix Metalloproteases-Mediated Cleavage on β-Dystroglycan May Play a Key Role in the Blood–Brain Barrier After Intracerebral Hemorrhage in Rats
por: Zhang, Xin, et al.
Publicado: (2019)

GlycoMine(struct): a new bioinformatics tool for highly accurate mapping of the human N-linked and O-linked glycoproteomes by incorporating structural features
por: Li, Fuyi, et al.
Publicado: (2016)

Identification of allosteric fingerprints of alpha-synuclein aggregates in matrix metalloprotease-1 and substrate-specific virtual screening with single molecule insights
por: Kamboj, Sumaer, et al.
Publicado: (2022)

Cancer-associated mutations in the canonical cleavage site do not influence CD99 shedding by the metalloprotease meprin β but alter cell migration in vitro
por: Bedau, Tillmann, et al.
Publicado: (2017)

Differential Expression of Matrix Metalloproteases in Human Fibroblasts with Different Origins
por: Lindner, Diana, et al.
Publicado: (2012)

The Matrix Metalloproteases and Endothelin-1 in Infection-Associated Preterm Birth
por: Olgun, Nicole S., et al.
Publicado: (2010)

Dysregulation of fibulin-5 and matrix metalloproteases in epithelial ovarian cancer
por: Manders, Dustin B., et al.
Publicado: (2018)

Matrix metalloprotease-1 inhibits and disrupts Enterococcus faecalis biofilms
por: Kumar, Lokender, et al.
Publicado: (2019)

Interleukin-17 and matrix metalloprotease-9 expression in the mycetoma granuloma
por: Siddig, Emmanuel Edwar, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_9q4ru23gc92581dsq8ruuhgocb