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A Quasi-direct LC-MS/MS-based Targeted Proteomics Approach for miRNA Quantification via a Covalently Immobilized DNA-peptide Probe

MicroRNAs (miRNAs) play a vital role in regulating gene expression and are associated with a variety of cancers, including breast cancer. Their distorted and unique expression is a potential marker in clinical diagnoses and prognoses. Thus, accurate determination of miRNA expression levels is a prer...

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Detalles Bibliográficos
Autores principales: Liu, Liang, Xu, Qingqing, Hao, Shuai, Chen, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515972/
https://www.ncbi.nlm.nih.gov/pubmed/28720752
http://dx.doi.org/10.1038/s41598-017-05495-7