Betulinic acid is a PPARγ antagonist that improves glucose uptake, promotes osteogenesis and inhibits adipogenesis

PPAR antagonists are ligands that bind their receptor with high affinity without transactivation activity. Recently, they have been demonstrated to maintain insulin-sensitizing and antidiabetic properties, and they serve as an alternative treatment for metabolic diseases. In this work, an affinity-b...

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Detalles Bibliográficos
Autores principales: Brusotti, Gloria, Montanari, Roberta, Capelli, Davide, Cattaneo, Giulia, Laghezza, Antonio, Tortorella, Paolo, Loiodice, Fulvio, Peiretti, Franck, Bonardo, Bernadette, Paiardini, Alessandro, Calleri, Enrica, Pochetti, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516003/
https://www.ncbi.nlm.nih.gov/pubmed/28720829
http://dx.doi.org/10.1038/s41598-017-05666-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516003/
https://www.ncbi.nlm.nih.gov/pubmed/28720829
http://dx.doi.org/10.1038/s41598-017-05666-6

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