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Dysregulated miRNAs and their pathogenic implications for the neurometabolic disease propionic acidemia
miRNome expression profiling was performed in a mouse model of propionic acidemia (PA) and in patients’ plasma samples to investigate the role of miRNAs in the pathophysiology of the disease and to identify novel biomarkers and therapeutic targets. PA is a potentially lethal neurometabolic disease w...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516006/ https://www.ncbi.nlm.nih.gov/pubmed/28720782 http://dx.doi.org/10.1038/s41598-017-06420-8 |