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Opinion: hazards faced by macromolecules when confined to thin aqueous films
Samples prepared for single-particle electron cryo-microscopy (cryo-EM) necessarily have a very high surface-to-volume ratio during the short period of time between thinning and vitrification. During this time, there is an obvious risk that macromolecules of interest may adsorb to the air–water inte...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516009/ https://www.ncbi.nlm.nih.gov/pubmed/28781996 http://dx.doi.org/10.1007/s41048-016-0026-3 |