A Predictive Mathematical Modeling Approach for the Study of Doxorubicin Treatment in Triple Negative Breast Cancer

Doxorubicin forms the basis of chemotherapy regimens for several malignancies, including triple negative breast cancer (TNBC). Here, we present a coupled experimental/modeling approach to establish an in vitro pharmacokinetic/pharmacodynamic model to describe how the concentration and duration of do...

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Detalles Bibliográficos
Autores principales: McKenna, Matthew T., Weis, Jared A., Barnes, Stephanie L., Tyson, Darren R., Miga, Michael I., Quaranta, Vito, Yankeelov, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516013/
https://www.ncbi.nlm.nih.gov/pubmed/28720897
http://dx.doi.org/10.1038/s41598-017-05902-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516013/
https://www.ncbi.nlm.nih.gov/pubmed/28720897
http://dx.doi.org/10.1038/s41598-017-05902-z

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