Concentration-Dependent Binding of Small Ligands to Multiple Saturable Sites in Membrane Proteins

Membrane proteins are primary targets for most therapeutic indications in cancer and neurological diseases, binding over 50% of all known small molecule drugs. Understanding how such ligands impact membrane proteins requires knowledge on the molecular structure of ligand binding, a reasoning that ha...

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Detalles Bibliográficos
Autores principales: Stock, Letícia, Hosoume, Juliana, Treptow, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516019/
https://www.ncbi.nlm.nih.gov/pubmed/28720769
http://dx.doi.org/10.1038/s41598-017-05896-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516019/
https://www.ncbi.nlm.nih.gov/pubmed/28720769
http://dx.doi.org/10.1038/s41598-017-05896-8

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