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Concentration-Dependent Binding of Small Ligands to Multiple Saturable Sites in Membrane Proteins

Membrane proteins are primary targets for most therapeutic indications in cancer and neurological diseases, binding over 50% of all known small molecule drugs. Understanding how such ligands impact membrane proteins requires knowledge on the molecular structure of ligand binding, a reasoning that ha...

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Detalles Bibliográficos
Autores principales:	Stock, Letícia, Hosoume, Juliana, Treptow, Werner
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516019/ https://www.ncbi.nlm.nih.gov/pubmed/28720769 http://dx.doi.org/10.1038/s41598-017-05896-8

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