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Blockade of Axl signaling ameliorates HPV16E6-mediated tumorigenecity of cervical cancer

Axl receptor tyrosine kinase is involved in the tumorigenesis and metastasis of many cancers. Axl expression was markedly higher in human papilloma virus type 16E6 (HPV16E6)-overexpressing HeLa (HE6F) cells and lower in HPV16E6-suppressing CaSki (CE6R) cells than in the controls. SiRNA-mediated knoc...

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Detalles Bibliográficos
Autores principales: Lee, Eun-Hee, Ji, Kon-Young, Kim, Eun-Mi, Kim, Su-Man, Song, Hyeong-Woo, Choi, Ha-Rim, Chung, Byung Yeoup, Choi, Hyo Jin, Bai, Hyoung-Woo, Kang, Hyung-Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516033/
https://www.ncbi.nlm.nih.gov/pubmed/28720772
http://dx.doi.org/10.1038/s41598-017-05977-8