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Meta‐analysis of two studies in the presence of heterogeneity with applications in rare diseases

Random‐effects meta‐analyses are used to combine evidence of treatment effects from multiple studies. Since treatment effects may vary across trials due to differences in study characteristics, heterogeneity in treatment effects between studies must be accounted for to achieve valid inference. The s...

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Detalles Bibliográficos
Autores principales: Friede, Tim, Röver, Christian, Wandel, Simon, Neuenschwander, Beat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516158/
https://www.ncbi.nlm.nih.gov/pubmed/27754556
http://dx.doi.org/10.1002/bimj.201500236