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Immune‐Array Analysis in Sporadic Inclusion Body Myositis Reveals HLA–DRB1 Amino Acid Heterogeneity Across the Myositis Spectrum

OBJECTIVE: Inclusion body myositis (IBM) is characterized by a combination of inflammatory and degenerative changes affecting muscle. While the primary cause of IBM is unknown, genetic factors may influence disease susceptibility. To determine genetic factors contributing to the etiology of IBM, we...

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Detalles Bibliográficos
Autores principales: Rothwell, Simon, Cooper, Robert G., Lundberg, Ingrid E., Gregersen, Peter K., Hanna, Michael G., Machado, Pedro M., Herbert, Megan K., Pruijn, Ger J. M., Lilleker, James B., Roberts, Mark, Bowes, John, Seldin, Michael F., Vencovsky, Jiri, Danko, Katalin, Limaye, Vidya, Selva‐O'Callaghan, Albert, Platt, Hazel, Molberg, Øyvind, Benveniste, Olivier, Radstake, Timothy R. D. J., Doria, Andrea, De Bleecker, Jan, De Paepe, Boel, Gieger, Christian, Meitinger, Thomas, Winkelmann, Juliane, Amos, Christopher I., Ollier, William E., Padyukov, Leonid, Lee, Annette T., Lamb, Janine A., Chinoy, Hector, Denton, Christopher, Gheorghe, Karina, Hilton‐Jones, David, Kiely, Patrick, Mann, Herman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516174/
https://www.ncbi.nlm.nih.gov/pubmed/28086002
http://dx.doi.org/10.1002/art.40045