Predicting phenotype from genotype: Improving accuracy through more robust experimental and computational modeling

Computational prediction yields efficient and scalable initial assessments of how variants of unknown significance may affect human health. However, when discrepancies between these predictions and direct experimental measurements of functional impact arise, inaccurate computational predictions are...

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Detalles Bibliográficos
Autores principales: Gallion, Jonathan, Koire, Amanda, Katsonis, Panagiotis, Schoenegge, Anne‐Marie, Bouvier, Michel, Lichtarge, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516182/
https://www.ncbi.nlm.nih.gov/pubmed/28230923
http://dx.doi.org/10.1002/humu.23193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516182/
https://www.ncbi.nlm.nih.gov/pubmed/28230923
http://dx.doi.org/10.1002/humu.23193

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