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Mitochondrial Cochaperone Mge1 Is Involved in Regulating Susceptibility to Fluconazole in Saccharomyces cerevisiae and Candida Species

MGE1 encodes a yeast chaperone involved in Fe-S cluster metabolism and protein import into the mitochondria. In this study, we identified MGE1 as a multicopy suppressor of susceptibility to the antifungal fluconazole in the model yeast Saccharomyces cerevisiae. We demonstrate that this phenomenon is...

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Detalles Bibliográficos
Autores principales: Demuyser, Liesbeth, Swinnen, Erwin, Fiori, Alessandro, Herrera-Malaver, Beatriz, Verstrepen, Kevin, Van Dijck, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516249/
https://www.ncbi.nlm.nih.gov/pubmed/28720726
http://dx.doi.org/10.1128/mBio.00201-17