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Mitochondrial Cochaperone Mge1 Is Involved in Regulating Susceptibility to Fluconazole in Saccharomyces cerevisiae and Candida Species
MGE1 encodes a yeast chaperone involved in Fe-S cluster metabolism and protein import into the mitochondria. In this study, we identified MGE1 as a multicopy suppressor of susceptibility to the antifungal fluconazole in the model yeast Saccharomyces cerevisiae. We demonstrate that this phenomenon is...
Autores principales: | Demuyser, Liesbeth, Swinnen, Erwin, Fiori, Alessandro, Herrera-Malaver, Beatriz, Verstrepen, Kevin, Van Dijck, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516249/ https://www.ncbi.nlm.nih.gov/pubmed/28720726 http://dx.doi.org/10.1128/mBio.00201-17 |
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