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Inhibition of Inflammasome-Dependent Interleukin 1β Production by Streptococcal NAD(+)-Glycohydrolase: Evidence for Extracellular Activity

Group A Streptococcus (GAS) is a common human pathogen and the etiologic agent of a large number of diseases ranging from mild, self-limiting infections to invasive life-threatening conditions. Two prominent virulence factors of this bacterium are the genetically and functionally linked pore-forming...

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Detalles Bibliográficos
Autores principales: Hancz, Dóra, Westerlund, Elsa, Bastiat-Sempe, Benedicte, Sharma, Onkar, Valfridsson, Christine, Meyer, Lena, Love, John F., O’Seaghdha, Maghnus, Wessels, Michael R., Persson, Jenny J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516252/
https://www.ncbi.nlm.nih.gov/pubmed/28720729
http://dx.doi.org/10.1128/mBio.00756-17