Cargando…

Dengue Virus Hijacks a Noncanonical Oxidoreductase Function of a Cellular Oligosaccharyltransferase Complex

Dengue virus (DENV) is the most common arboviral infection globally, infecting an estimated 390 million people each year. We employed a genome-wide clustered regularly interspaced short palindromic repeat (CRISPR) screen to identify host dependency factors required for DENV propagation and identifie...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, David L., Cherepanova, Natalia A., Bozzacco, Leonia, MacDonald, Margaret R., Gilmore, Reid, Tai, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516256/
https://www.ncbi.nlm.nih.gov/pubmed/28720733
http://dx.doi.org/10.1128/mBio.00939-17