Multiple-attempt dynamics of type IA topoisomerases revealed in an orthogonal single-molecule experiment

Topoisomerases are enzymes involved in maintaining the topological state of cellular DNA. Despite many structural, biophysical, and biochemical studies, their dynamic characteristics remain poorly understood. Recent single molecule experiments revealed that an important feature of the type IA topois...

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Detalles Bibliográficos
Autores principales: Gunn, Kathryn H., Marko, John F., Mondragón, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516274/
https://www.ncbi.nlm.nih.gov/pubmed/28414321
http://dx.doi.org/10.1038/nsmb.3401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516274/
https://www.ncbi.nlm.nih.gov/pubmed/28414321
http://dx.doi.org/10.1038/nsmb.3401

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