Sex is a moderator of the association between NOS1AP sequence variants and QTc in two long QT syndrome founder populations: a pedigree-based measured genotype association analysis

BACKGROUND: Sequence variants in the NOS1AP gene have repeatedly been reported to influence QTc, albeit with moderate effect sizes. In the long QT syndrome (LQTS), this may contribute to the substantial QTc variance seen among carriers of identical pathogenic sequence variants. Here we assess three...

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Detalles Bibliográficos
Autores principales: Winbo, Annika, Stattin, Eva-Lena, Westin, Ida Maria, Norberg, Anna, Persson, Johan, Jensen, Steen M., Rydberg, Annika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516337/
https://www.ncbi.nlm.nih.gov/pubmed/28720088
http://dx.doi.org/10.1186/s12881-017-0435-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516337/
https://www.ncbi.nlm.nih.gov/pubmed/28720088
http://dx.doi.org/10.1186/s12881-017-0435-2

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